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ISSN: 2644-1217

Open Access Journal of Complementary & Alternative Medicine

Research ArticleOpen Access

Pharmacological Effects of withanolides Volume 1 - Issue 5

Zheng Wei1, Tingting Li1, Huilin Su2, Qiuhong Wang2* and Haixue Kuang1*

  • 1School of Pharmacy, Heilongjiang University of Chinese Medicine, China
  • 2School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, China

Received: November 13, 2019;   Published: November 26, 2019

*Corresponding author: Haixue Kuang, School of Pharmacy, Heilongjiang University of Chinese Medicine, 24 He ping Road, Xiang fang District, Harbin 150040, Heilongjiang, China

Qiuhong Wang, School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, 280 Outer Ring Road, University Town, Guangzhou 510006, China

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Withanolides is a class of active compounds widely found in Solanaceae plants. In traditional applications, it has a long history and a wide range of functions. With the progress of drug structure and pharmacological research, more and more reports point to its excellent anticancer effect. Solanaceae is widely distributed, providing a large number of sources for the structure and pharmacological research of its natural products. At the same time, in the light of market demand, the circulation of such medicinal materials is enormous. Based on the pharmacological action of inhibiting NF-κB signaling pathway, withanolides has become a research hotspot in natural medicine. Perhaps combining traditional clinical practice will point out a new research direction to provide basic information for the development of new drugs for difficult cases.

Keywords: Withanolides; Withaferin A; Anti-inflammatory ; Anti-tumor; NF-κB

Abstract| Introduction| Discussion and Future Direction| References


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