Withanolides is a class of active compounds widely found in Solanaceae plants. In traditional applications, it has a long history
and a wide range of functions. With the progress of drug structure and pharmacological research, more and more reports point
to its excellent anticancer effect. Solanaceae is widely distributed, providing a large number of sources for the structure and
pharmacological research of its natural products. At the same time, in the light of market demand, the circulation of such medicinal
materials is enormous. Based on the pharmacological action of inhibiting NF-κB signaling pathway, withanolides has become a
research hotspot in natural medicine. Perhaps combining traditional clinical practice will point out a new research direction to
provide basic information for the development of new drugs for difficult cases.