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ISSN: 2644-1217

Open Access Journal of Complementary & Alternative Medicine

Research ArticleOpen Access

Experimental Animal Model for Acute Toxicity Testing with Natural Products Volume 2 - Issue 2

Emerson Barbosa da Silva*, Patrick Gabriel dos Santos Pessini, Camila dos Santos Chagas, Daniel Santos Neves, Rodrigo Pereira Barbosa, Giuliana petri and Fernando Luiz Affonso Fonseca

  • University Health Center ABC , Lauro Gomes Avenue, Brazil

Received: January 20, 2020;   Published: February 11, 2020

*Corresponding author: University Health Center ABC-Lauro Gomes Avenue, 2000-Vila Sacadura Cabral- Santo André-SP -Zip Code: 09060-870, Brazil

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BALB/c mice are often used in laboratory researches and its methodology needs to be standardized. A number of mice previously inoculated with Ehrlich’s tumor were used under appropriate conditions to collect blood samples and analyze hematological parameters in automated and semi-automated equipment and allow this methodology to be made. The study successfully defined and established the methodology needed to obtain reference values for hematological parameters and to assist researchers develop their own methodology about animal handling and group management in experiments.

Keywords: Ehrlich tumor carcinoma; Experimental animal model toxicity

Abstract| Introduction Method Conclusion References


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