Cytoprotective Effect of Zingiber Officinale extract on
Alcohol Induced Gastric Lesion in Mice
Volume 2 - Issue 3
Samia Elzwi1* and Amina Elzwi2
- 1MSc Lecture at pharmacology department, University of Benghazi, Libya
- 2Pharmacy doctor at faculty of pharmacy, University of Benghazi, Libya
Received: May 11, 2020; Published: May 21, 2020
*Corresponding author: Samia Elzwi, MSc Lecture at pharmacology department, University of Benghazi, Libya
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Abstract
Ginger is a perennial plant that grows in India, China, Mexico and several other countries. The rhizome is used as both spice
and in herbal medicine. Many studies have been done on pharmacological effect of ginger extract and our paper has been focused
on cytoprotective effect of ginger on ethanol induced gastric injury in mice. Many drugs have been used in the treatment of peptic
ulcer but each of them associated with different side effect so trends today toward use of herbal medicine which was associated
with adverse effect. Ginger hydroalcoholic extract contain different consistent with anti-ulcer properties like 6-Gingersulfonic
acid and three monoacyldigalactosyl glycerol including ginger glycolipid A. B. C .The mechanism of ginger extract may be due to
counteracting the active oxidant radicals, decreasing mucosal cell shedding and thicking the mucus membrane so ginger extract has
antiulcer properties when used in accurate dose and accurate duration.
Keywords: Cytoprotective effect; Ethanol; Ginger hydroalcoholic extract; Mice; Zingiber Officinale
Abstract|
Introduction
Mechanism of Gastric Effect of Ginger
Method
Results
References