The gastric ulcer is epidemic disease in many countries the main cause of the disease is helicobacter pylori which transfers by
polluted foods. Many protocols and guidelines for the treatment and the most common guidelines is triple therapy Amoxicillin,
Clarithromycin and proton pump inhibitors, but now the resistant to this protocol due to irrational use of the antibiotics. The study
was done on the Helicobacter pylori by Kirby-Bauer sensitivity Test method which clarify that one of the components of the triple
therapy clarithromycin, which failed to pass the test which indicates the retarding in the recovery to H. Pylori that open road to put
new guidelines for H. Pylori especially in countries widely and irrationally use antibiotics. The study recommended that to put new
guidelines and studies about the growing of resistant to antibiotics.
Keywords: H. Pylori; Protocol; Treatment; Antibiotic; Amoxicillin; Resistance; New Guidelines