The Contribution of Liquid Biopsy in Diagnosis and Prognosis of Colorectal Cancer Volume 4 - Issue 5

Nora Tu¹*, Zahidul Islam¹, Mackenzie Henderson^1,2 and Maribel Salas^1,3

• ¹Global Epidemiology Department, Daiichi Sankyo, USA
• ²Rutgers Institute for Pharmaceutical Industry Fellowships, Rutgers University, USA
• ³Center for Clinical Epidemiology and Biostatistics (CCEB)/Center for Pharmacoepidemiology Research and Training (CPeRT), University of Pennsylvania Perelman School of Medicine, USA

Received:August 5, 2021   Published: August 19, 2021

Corresponding author: Nora Tu, Global Epidemiology Department, Daiichi Sankyo, 211 Mount Airy Road, Basking Ridge, NJ, USA

DOI: 10.32474/OAJOM.2021.04.000199

 

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Abstract

Colorectal cancer is one of the most leading causes of death worldwide. Furthermore, early-onset colorectal cancer increased the last decades, affecting both males and females below the age of 50, and has lower survival rates. Prevention and detection at early stages contributes to reduced mortality rates. Liquid biopsy is a powerful tool in prevention and prediction of the disease. Liquid biopsy refers to collection of blood and then, detection and study of circulating tumor cells, circulating-tumor DNA as well as exosomes. This review reports major and recent issues of liquid biopsy and the contribution as diagnostic tool in colorectal cancer.

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