A Multilevel Mediation Model to Investigate the Effect of
Sleep Quality as a Mediation Factor on the Association
between Secondhand Smoking and Depressive Symptoms
Volume 2 - Issue 1
Alfred K Mbah*
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- Department of Epidemiology and Biostatistics, University of South Florida, USA
*Corresponding author:
Alfred K Mbah, University of South Florida, College of Public Health, Department of Epidemiology and
Biostatistics, Tampa, USA
Received: December 17, 2019; Published: January 08, 2020
DOI: 10.26717/CTBB.MS.ID.000130
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Abstract
We investigate in this study the impact of sleep quality as a mediating factor in the association between second hand smoking
and depressive symptoms. The study included 196 pregnant women interviewed during and after pregnancy. A multilevel mediation
model was applied to the data. Our results suggested that exposure to second hand smoking (ETS) positively predicted sleep quality
0.314, 95% CI [0.124, 0.504], ρ = 0.001 .
In turn, sleep quality was positively related to the depressive symptoms 0.551, 95% CI [0.122, 0.98], ρ = 0.012 . As a result, the
between-cluster indirect effect of ETS on depressive symptoms was 0.173 (= 0.314 × 0.551). The distribution of the product of
the coefficients 95% CI for the indirect effect was [0.028, 0.375], which did not contain zero. This indicates that the indirect effect
of ETS on depressive symptoms through sleep quality was significantly different from zero. Therefore, the results show that the
association of ETS on depressive symptoms was completely mediated by sleep quality. These findings highlight the need to develop
interventions for pregnant women who are exposed to low sleep quality. Reducing exposure to environmental tobacco smoke in
the antepartum period may be an important step in mitigating the risk of peri-natal and post-patum depression among vulnerable
populations. We think that improving sleep architecture may improve the quality of life for pregnant women and their infant.
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