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ISSN: 2637-4579

Open Access Journal of Biomedical Engineering and Biosciences

Research Article(ISSN: 2637-4579)

Biomechanical Engineering Analysis of Glaucoma Micro Stent Implant with Check Valve for Intraocular Pressure Reduction (IOP) by Finite Element Method (FEM)

Volume 1 - Issue 5

Ö Karaçalı*

  • Author Information Open or Close
    • Department of Mechanical Engineering, Istanbul University, Turkey

    *Corresponding author: Özdoğan Karaçalı, Department of Mechanical Engineering, Faculty of Engineering, Istanbul University, Avcılar, Istanbul, Turkey

Received: March 13, 2018;   Published: March 20, 2018

DOI: 10.32474/OAJBEB.2018.01.000122

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Abstract

Biomechanical factors affect the design model of glaucoma micro stent (GMS) geometry, material and shape in correcting treatment of high intraocular pressure (IOP). The goal of this research was to characterize the biomechanics of the GMS using computational finite element method. In this research, the model for nano-composite materials will be investigated for analyzing the material behavior of the GMS with check valve used in the intraocular fluid evacuation system which is not made until now to control the intraocular pressure. It has not been reported about what impacts on GMS with check valve design and material selection to ensure discharge of ocular fluid in intraocular pressure (IOP), ensuring fluid flow continuity. Finite element Analysis simulation methodology for realization of accurate structural and aqueous humor (AH) behavior micro model during this analysis provided valuable results of useful data of GMS material behavior that are time consuming and expensive to determine otherwise. The check valve provided a control mechanism for AH pressure to regulate the IOP. For this reason, material deformation von-Mises and fluid flow behaviors model was developed. To achieve these, finite element analysis were employed to calculate compressive stresses and equivalent von-Mises stress criteria as well as the analysis by the strength of material’s experimental procedure in laboratory conditions. A finite element analysis (FEA) of GMS under very low cyclic loading conditions is presented. The results of modeling were verified with experimental data for biocompatible and biodegradable GMS from nano-composite material. This research provided a data set for preventing glaucoma disease and improving intraocular tension by new design of GMS.

Keywords: Glaucoma micro stent; Finite Element Analysis (FEA); Biomechanics; Von-Mises stress; Strain

Abbrevations: GMS: Glaucoma Micro Stent; IOP: Intraocular Pressure; AH: Aqueous Humor; FEA: Finite Element Analysis; FE: Finite Element

Abstract| Introduction| Materials and Methods: Biomechanical Models of GMS| Conclusion| Acknowledgement| References|

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