Lipomas are the most common mesenchymal tumours. They arise from primordial adipocytes and gradually increase in size with age. They usually develop as well-circumscribed, encapsulated masses that are freely mobile beneath the skin. Lipomas can occur in many locations all over the body, but most commonly in the subcutaneous tissue of the head, neck, shoulders and back. Lesions that are larger than 5 cm are termed as giant lipomas [1]. Giant lipomas of the upper extremity are rare and require an appropriate workup. This should be followed by adequate open surgical excision and repeat examination over time to monitor for recurrence.
A 45-year-old gentleman presented with chief complaints of a large swelling over the left upper limb for 20 years. The swelling was initially small to begin with but increased gradually
over the past 20 years to reach the present size. There were no associated complaints of weakness, numbness, difficulty in upper limb movements, loss of sensations or overlying skin colour changes. There was no history of any other swellings over the body. Patient was not having any associated comorbidities. On examination, a large pedunculated swelling of size 25x 15cm over left arm extending from proximal one third to distal third of arm. No tenderness or local rise in temperature was present. Swelling was mobile with no fixity to skin, muscle or bone. Ultrasonography of local swelling was suggestive of lipoma. Fnac was done which was suggestive of lipoma. Patient underwent an elective open excisional surgery for the swelling under general anaesthesia. Patient was extubated and tolerated the procedure well. Histopathology reports were confirmatory for lipoma. Patient was discharged uneventfully (Figures 1-7).
The standard management of giant lipomas is open excision
[2]. A full histopathology report of the specimen is required to
determine the possible need for any further treatment, as the main
concern while evaluating a giant lipoma in the upper extremity
is to rule out malignancy. Excisional surgery although being the
standard treatment of giant lipomas also involves large incisions
that may be associated with complication like infection, seroma
or haematoma, as well as an unacceptable scar. Liposuction was
employed for giant lipomas with added advantage of avoiding
scar formation, but it may be complicated by skin puckering and
dimpling as well as chances of recurrence [3]. It is suggested that
if a fatty subcutaneous tumour is more than 10 cm in diameter and
has shown a rapid growth in recent months, then the possibility
of liposarcoma must be considered [4,5]. Clinically, the age of the
patient and onset of symptoms must be thoroughly evaluated, and
if possible, a magnetic resonance imaging or a tissue sample must
be obtained in order to prove that the tumour is not malignant.
Although if tumour is proved negative by these measures, it does
not exclude the probability [6-8].
Giant lipomas are of size more than 5cm and warrant a workup
for malignancy. They rarely occur in upper limbs, unlike in our
case, making it a rare finding. All lipomas in the upper extremities
measuring larger than 5 cm in a single dimension should be
surgically removed due to malignant potential.