Magnesium Sulphate Agitation Management Effectiveness in Cases of Endoscopic Sinus Surgical Interventions

Volume 2 - Issue 2

Mohamed Sayed Fahim*

Received: September 18, 2019;   Published: September 23, 2019

DOI: 10.32474/GJAPM.2019.02.000131

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Abstract

Background: A bloodless field is one of the aims to enhance the visualization during the endoscopic sinusoidal procedure that is usually achieved by controlled hypotension permitting easier dissection. The value of magnesium sulfate as an agent that could reduce the agitation issues postoperative still requires research efforts to be compared to placebo as regards endoscopic sinus surgical interventions.

Aim: To investigate the effectiveness of magnesium sulphate in treatment of postoperative agitation following functional endoscopic sinus surgery.

Methodology: A prospective clinical research trial that recruited 210 research study subjects scheduled for sinus endoscopic surgeries Cases have been categorized in a random manner into two research groups equally numbered one research group have been administered intraoperative magnesium sulphate and the other group 0.9% saline solution.

Results: The comparative statistical analysis between magnesium group and control group regarding RASS score(Richmond agitation-sedation scale) at different time of measurement and incidence of agitation at 0 min in which the RASS score was statistically significantly lower among magnesium research group at 0, 5, 10, 15, 20, 25, 30, total (p values 0.008, <0.001, <0.001, 0.005, 0.008, 0.013, 0.020, <0.001 consecutively) Incidence of agitation at 0min was statically significantly lower among the magnesium research group (p value=0.019)

Conclusion: Magnesium sulphate administration is a useful agent in reducing the agitation issues in endoscopic sinus surgical procedure; however, the current research study results should be verified by future research efforts in a multicenter manner.

Keywords: Magnesium sulphate; Agitation; Endoscopic sinus surgical interventions

Abstract| Introduction| Methodology| Results| Discussion| Conclusions and Recommendations for Future Research| References|