Background: A bloodless field is one of the aims to enhance the visualization during the endoscopic sinusoidal procedure that is
usually achieved by controlled hypotension permitting easier dissection. The value of magnesium sulfate as an agent that could
reduce the agitation issues postoperative still requires research efforts to be compared to placebo as regards endoscopic sinus
Aim: To investigate the effectiveness of magnesium sulphate in treatment of postoperative agitation following functional endoscopic
Methodology: A prospective clinical research trial that recruited 210 research study subjects scheduled for sinus endoscopic
surgeries Cases have been categorized in a random manner into two research groups equally numbered one research group have
been administered intraoperative magnesium sulphate and the other group 0.9% saline solution.
Results: The comparative statistical analysis between magnesium group and control group regarding RASS score(Richmond
agitation-sedation scale) at different time of measurement and incidence of agitation at 0 min in which the RASS score was statistically
significantly lower among magnesium research group at 0, 5, 10, 15, 20, 25, 30, total (p values 0.008, <0.001, <0.001, 0.005, 0.008,
0.013, 0.020, <0.001 consecutively) Incidence of agitation at 0min was statically significantly lower among the magnesium research
group (p value=0.019)
Conclusion: Magnesium sulphate administration is a useful agent in reducing the agitation issues in endoscopic sinus surgical
procedure; however, the current research study results should be verified by future research efforts in a multicenter manner.