Hepatitis of Halothane: A Fatality to Avoid; A Case Report Volume 2 - Issue 5

Jbili N¹*, Bibiche L¹, Jebbar N¹, Maaroufi A¹, Diai A², Chkoura K², Kechna H² and Laoutid J²

• ¹Pole of anesthesia, resuscitation and emergencies, Meknes Military Hospital, Morocco
• ²Faculty of Medicine and Pharmacy of Rabat, Mohammed V University, Morocco

Received: January 31, 2020;  Published: February 11, 2020

Corresponding author: Nabil Jbili, Pole of Anesthesia, Resuscitation and Emergencies, Moulay Ismail-Meknes Military Hospital, Morocco

DOI: 10.32474/GJAPM.2020.02.000147

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Summary

We report the observation of a 56-year-old female patient, with no specific medical history, operated on for acute cholecystitis. One week after the intervention, she presented a fatal fulminant hepatitis in less than two weeks, associating a deterioration of the general state with jaundice cutaneous mucosal frank, cytolysis and cholestasis important in addition to a deep hypo albuminemia and a very low prothrombin level. The toxicity of halothane has been incriminated due to the negativity of the etiological balance. Like the literature and this clinical case, the still frequent use of halothane in several countries must be reviewed.

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