Estimation of the Predictive Factors of Myocardial Ischemic Preconditioning in Elective Surgical Patients Volume 3 - Issue 2

Zaily Fuentes Díaz¹*, Gonzalo Fabián Orga García², Orlando Rodríguez Salazar³, Jorge Lozano Casanova⁴, Tania Puerto Pérez⁵

• ¹Specialist in Comprehensive General Medicine, Doctor of Medical Sciences, María Curie Cancer Hospital, Cuba
• ²Specialist in Anesthesiology and Reanimation, University of Medical Sciences, Uruguay
• ³Specialist in Comprehensive General Medicine, Master’s in medical emergencies. Manuel Ascunce Domenech University Hospital, Cuba
• ⁴Degree in biochemistry, University of Medical Sciences of Camagüey, Cuba
• ⁵First Degree Specialist in Biostatistics, University of Medical Sciences of Camagüey, Cuba

Received: April 07, 2020;  Published: April 24, 2020

Corresponding author: Zaily Fuentes Diaz, Specialist in Comprehensive General Medicine, Second Degree Specialist in Anesthesiology and Reanimation, Doctor of Medical Sciences, Assistant Professor and Researcher, María Curie Cancer Hospital, Cuba

DOI: 10.32474/GJAPM.2020.03.000156

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Abstract

Introduction: the physiological response to the aggression produced by the surgical trauma provides the effective treatment capacity in case of complications. Surgical intervention causes endocrine, metabolic, autonomic, immunological, and hematological changes.

Objective: to estimate the predictive factors of the second window of myocardial ischemic preconditioning in the patients proposed for elective surgical interventions.

Material and Methods: A quasi-experimental study was carried out in the period January to December 2019 at the Maria Curie Cancer Hospital in Camagüey with patients who met inclusion and exclusion criteria in preoperative consultation in the research period, to whom preconditioning was applied. Ischemic two hours before surgery. Chi squared and logistic regression was calculated as appropriate.

Results: Predictive factors such as essential arterial hypertension odds ratio 16,632, diabetes mellitus 12,157, age 60 years and over with odds ratios of 8,035, heart failure odds ratio 6,433, cerebrovascular disease odds ratio 6,135, and chronic kidney disease were estimated. Odds ratio 5,800 and chronic obstructive pulmonary disease with odds ratio 5,738.

Conclusion: the predictive factors of the second window of ischemic preconditioning were independent predictors of risk in elective surgical patients.

Keywords:Preconditioning; Elective surgical patient; Surgical stress; Predictive factors

Abstract| Introduction| Material and Methods| Results and Discussion| Conclusion| Acknowledgement| Conflict of interest| References|