Detox - Haemofiltration for The Neuroleptic Malignant Syndrome

Volume 1 - Issue 2

Juan F Martin Lazaro¹*, Marc Brown¹, Emily Gould¹, Johann Grundlingh¹, Michal Brys Ieva Norkiene¹, Joaquim Cevallos¹, James Napier¹, Khyati Lad² and Jacek Jablonski³

Received: April 04, 2019;   Published: April 23, 2019

DOI: 10.32474/GJAPM.2018.01.000111

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Abstract

Removal of serum toxins using haemofiltration with human albumin has been demonstrated to be a useful option for the treatment of a patient following the ingestion of unknown substance. Here, a case is described in which a patient presented with symptoms of neuroleptic malignant syndrome after ingesting an unknown Nigerian herbal remedy. Albumin enhanced continuous veno-venous haemodialysis has been previously used for intoxications. When combining continuous renal replacement therapy with albumin, the toxins are bound to the larger molecule which prevents the toxins moving through the filter; allowing for clearance from the blood. We suggest that Intensive Care Units should consider basic tools, such as detox haemofiltration when an unknown poison is suspected.

Abstract| Introduction| Case Report| Methods| Discussion| Conclusion| References|