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ISSN: 2637-4706

Drug Designing & Intellectual Properties International Journal

Research Article(ISSN: 2637-4706)

Cytotoxicity and Antioxidant Potentials of Barringtonia Asiatica Essential Oil

Volume 2 - Issue 2

Isaac John Umaru1,2*, Chinedu Imo2, Kayode Arowora2, Silas Verwiyah Tatah2 and Hauwa A Umaru3

  • Author Information Open or Close
    • 1Faculty of Resource Science and Technology, University of Malaysia Sarawak, Malaysia
    • 2Department of Biochemistry, Federal University, Nigeria
    • 3Department of Biochemistry, Modibo Adama University of Technology, Nigeria

    *Corresponding author: Isaac John Umaru, Faculty of Resource Science and Technology, University of Malaysia Sarawak, Malaysia

Received: August 11, 2018;   Published: August 21, 2018

DOI: 10.32474/DDIPIJ.2018.02.000131

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Abstract

Essential oils are liquid mixture of volatile compound obtained from aromatic plants. It was observed that many essential oils have antioxidant properties and can present antimicrobial activities. The Aim of the present study were:

a) to determine the cytotoxicity lethality of the leafs and stem-bark of Barringtonia asiatica using brine shrimp (Artimia salina).

b) to evaluate the antioxidant potential of composition of the leaf and stem-bark essential oil using the DPPH (2,2-diphenyl-1- picrylhydrazyl) free radical scavenging assay. The essential oil exhibited a mild toxicity and significant IC50 of 36.55μg/mL and 22.10μg/mL value of antioxidant potential leaf and stem-bark of Barringtonia asiatica respectively.

Keywords: Barringtonia asiatica; essential oil; cytotoxicity; antioxidant

Abstract| Introduction| Materials and Methods| Results| Discussion| Conclusion| Acknowledgement| Refernces|

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