Phytochemical and Antioxidant Activities of Different
Fractional Extracts of Alstonia scholaris Linn
Volume 2 - Issue 3
Md Abdul Kaium Siddiki and Md Shahidul Islam*
- Department of Pharmacy, University of Science and Technology Chittagong (USTC), Bangladesh
Received: May 13, 2020; Published: May 26, 2020
*Corresponding author: Md Shahidul Islam, Department of Pharmacy, University of Science and Technology Chittagong (USTC),
Chattogram, Bangladesh
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Abstract
Alstonia scholaris Linn is popularly known as the “Chatim” or the Devil tree, which are used as a well-known remedy for the
treatment of various types of disorders in the Ayurvedic, Homoeopathic and Folklore system of medicine in Bangladesh, India
and many others countries. Alstonia scholaris is mainly used for the treatment of diarrhoea and malaria as a tonic, febrifuge,
emmenagogue, anticholeric and vulnerary. Considering the medical importance and source of origin, the plant Alstonia scholaris
has been subjected for fractionation with different solvents. The different fractions of ethanolic extract of Alstonia scholaris were
evaluated for antioxidant activity as well as biological activity. Phytochemical properties of leaves of Alstonia scholaris were also
investigated. The different solvent fractions showed the presence of tannins, glycosides, steroids, and alkaloids. The different
fractions of ethanolic extract of Alstonia scholaris were evaluated for the total phenolic content, total flavonoid content, reducing
power capacity, total antioxidant activity and DPPH radical scavenging activity. From the result on the various antioxidant activity
tests, it was found that Dia-ion resin adsorbed fraction showed the highest value, followed by petroleum ether fraction, ethyl acetate
fraction and chloroform fraction. Overall results of the antioxidant evaluation and various biological screening tests were found
satisfactory and may encourage researcher to use this plant as a source of potent antioxidant food material as well as bioactive toxic
compounds to be used in therapeutic drugs preparation.
Keywords: Phytochemistry; Antioxidant Activities; Alstonia scholaris; Chloroform
Abstract|
Introduction
Methods and Materials
Process of Extraction
Determination of Total Antioxidant Activity
Determination of Dpph Radical Scavenging Activity
Results & Discussion
Total Flavonoid Content
Reducing Power Capacity Content
Total Antioxidant Activity
DPPH Radical Scavenging Activity
Conclusion
References