email   Email Us: info@lupinepublishers.com phone   Call Us: +1 (914) 407-6109   57 West 57th Street, 3rd floor, New York - NY 10019, USA

Lupine Publishers Group

Lupine Publishers

  Submit Manuscript

ISSN: 2637-4579

Open Access Journal of Biomedical Engineering and Biosciences

Mini Review(ISSN: 2637-4579)

A Computational Simulation of Bladder Cancer Growth

Volume 1 - Issue 5

Chia Jung Chan*1, Tin-Kan Hung2 and Chih-Han Chang11*

  • Author Information Open or Close
    • 1Department of Biomedical Engineering, National Cheng Kung University, Taiwan
    • 2Department of Bioengineering, University of Pittsburgh, Pittsburgh, USA

    *Corresponding author: Chia-Jung Chang, Department of Biomedical Engineering, National Cheng Kung University, Tainan, ROC, Taiwan

Received: March 12, 2018;   Published: March 16, 2018

DOI: 10.32474/OAJBEB.2018.01.000121

Full Text PDF

To view the Full Article   Peer-reviewed Article PDF

Abstract

A three-dimensional (3D) simulation is established for bladder cancer development. Distribution of cancer cells is obtained by using a Monte Carlo procedure. The tumor blocks are meshed with uniform hexahedral microelements. Each element is assessed on its cancer growth probability (CGPi) during a time interval. The CGPi value is related to the growth of tumors. In this study, the exponential growth of tumors is considered. Factors associated with the immune system, medication, and other cell conditions were not yet included. The 3D computational modeling is anticipated to develop patient-specific simulation towards clinical management.

Keywords: Biological modeling; Bladder cancer; Monte Carlo method; Simulation

Abbrevations: V: Tumor volume; SGR: Specific Growth Rate; DT:Tumor Volume Doubling Time; CGPi : Cancer growth Probability; CAi : Cancer Attribute

Abstract| Introduction| Conclusion| Acknowledgement| References|

https://www.high-endrolex.com/21