Therapeutic Effect of Barley Grains powder (Hordeum vulgare L.) Among Sudanese Patients with Proteinuria Admitted at Ibn Sina Hospital in Khartoum State - Pilot study 2018

Volume 2 - Issue 5

Nahla A Khairy¹, Ibrahim A Ali²*, Mohamed I Eisa³, Shihab Eldin S Dishean⁴ and Omer A Musa⁵

Received: April 03, 2020;   Published: June 23, 2020

DOI: 10.32474/JUNS.2020.02.000148

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Abstract

Background: Proteinuria is very common in Glomerular diseases like membranous glomerulonephritis, focal segmental glomerulonephritis and minimal change disease. Severe proteinuria can cause nephrotic syndrome in which there is worsening swelling of the body. Barley grains were used to treat the proteinuria but not been recommended formally to be used.

Objectives: This study aimed to determine the effect of Barley grains powder (Hordeumvulgare L.) among Sudanese patients with Proteinuria admitted at Ibn Sina hospital in Khartoum state.

Methods: This is an analytical, cross-sectional hospital based study performed in Ibn Sina hospital in Khartoum state capital of Sudan during 2018-2019 in Sudanese patients above of age range (20 - 80 years old) who have documented renal impairment with significant proteinuria and have no extra renal cause of proteinuria. The patients were given barley for one week. In a dose of full tea glass of barely in three tea glasses of water (one tea glass equal 750 ml of water and 50 mg of barely). 24 hour’s urine and Blood samples for each patient was collected before and after barley administration and then the samples were sent to the laboratories for urinary protein estimation, serum albumin and renal functions test.

Results: The mean of urinary proteins before the barley administration was found to be 300.1389 mg/dl SD while the mean after barley administration was 248.74. With regards to 24 hours urine proteins; before intervention the mean was found to be 3.3934 g/day while the mean after intervention was 2.6433 g/day with significant p value (0.016). The level of serum albumin was found to be higher after administration of Barley with mean (2.6083 g/dl) compared to the mean after intervention (3.0500 g/dl) with significant p value 0.031.

Conclusion: Barley was found to be effective therapy for treatment of patients with proteinuria

Keywords: Barley; Proteinuria; Sudan

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