The superficial bladder cancer is associated with high risk of recurrence and progression, necessitating lengthy follow up
and repeated endoscopic treatments. White light cystoscopy (WLC) is the current gold standard for the diagnosis, treatment and
surveillance, however the sensitivity and specificity isn’t perfect with risk of missing some tumours. A photodynamic diagnosis
(PDD) using Blue-light cystoscopy is a novel concept proposed to overcome the WLC shortcomings. This critical review synthesizes
the evidences on the effectiveness of Blue light cystoscopy (BLC) for the diagnosis of non-muscle invasive bladder cancer (NMIBC),
and the impact of photodynamic diagnosis on the recurrence rate and progression of superficial bladder cancer..