The incidental detection of small renal tumors is increasing. Over 75% of such renal tumors, smaller than 4 cm are malignant.
Therefore the use of renal biopsy increased during the last decades. It is well tolerated and has a high diagnostic yield. Endoscopic
ultrasound-guided fine needle aspiration represents a new option for renal tissue sampling, especially in those patients who
simultaneously present suspected neoplastic lesions both in the kidney and in other anatomical districts such as lungs. We present
two cases with concomitant intrathoracic and left kidney lesion, in which sampling of renal nodule by EUS-FNA changed the
Keywords: Renal mass biopsy; EUS-FNA; Mediastinal adenopathy; Lung cancer