Process for Preparation of Vitamin C and Method for Determination of Vitamin C in Tablets

Krishnasarma pathy*

Received: June 05, 2018;   Published: June 15, 2018

DOI: 10.32474/SCSOAJ.2018.01.000114

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Abstract

Procedure for calcium ascorbate (VITAMIN-C) includes such technological steps as reaction of ascorbic acid on calcium carbonate in water. In recent years, the determination of vitamin C has become an important subject in the field of biochemistry and commercial foods. This is because vitamin C plays an important role in maintaining human health. Due to the importance of vitamin C in human beings, the quantitative analysis of vitamin C has gained a significant increase in several areas of analytical chemistry such as pharmaceutical and food applications. There are numerous methods for the determination of vitamin C in a variety of natural samples, biological fluids and pharmaceutical formulations. The prepartaion method and methods for the determination of vitamin C are spectrophotometric methods and non-spectrophotometric methods (Arya and Mahajan, 1997). For non-spectrophotometric methods are such as high-performance liquid chromatography (HPLC), titration, enzymatic method and fluorometry (Arya, Mahajan and Jain, 2000). Direct spectrophotometry also has been applied to determine the vitamin C content in soft drinks, fruit juices, and cordials after correction for background absorption in the UV region.

Abbreviations: FIA: Flow Injection Analysis; HPLC: High Performance Liquid Chromatography HMF: Hydroxymethylfurfural; AIDS: Acquired Immuno Deficiency Syndrome; FDA: Food and Drug Administration

Abstract| Introduction| Experimental Procedures| Flow Injection Analysis (FIA)| Ultraviolet (UV) Spectrophotometry| Fluorometric Method| Materials and Methods| Experimental Procedure| Result and Discussion| Conclusion| References|