Acute liver failure and hyperthyroidism are not typically common, although some cases have been reported. The mechanisms
involved and optimal management are not well-defined. This article presents the case of a 32-year-old African American female
referred for evaluation of abdominal pain and jaundice, with a past medical history of systemic lupus erythematosus and Grave’s
disease. She had thyrotoxicosis after administration of contrast and developed acute liver failure culminating in liver transplant and
subsequent total thyroidectomy with a favorable outcome.