The Genome of Polycystic Ovary

Kadreya Elmorshedy *

Received: February 25, 2019;   Published: March 01, 2019

DOI: 10.32474/OAJRSD.2019.02.000137

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Abstract

Polycystic ovary syndrome (PCOS) is a complex disease whose clinical manifestations and definition are an ongoing controversy among researchers. PCOS is the most common endocrinopathy in females in the childbearing period resulting in reproductive and metabolic disorders. A large number of genomic variants have been associated with PCOS, no single gene has emerged as a convincing biomarker thus far. This may be attributed to a large amount of heterogeneity observed in this disorder. This review presents an overview of the polymorphisms in genes related to insulin signaling and their association with PCOS and its related traits.

Keywords:Genome; PCOS; Ovary; Gene; A Metabolic Disorder

Abstract| Introduction| Genetic Investigations| Insulin Resistance and PCOS| New Avenues in PCOS Research| Conclusion| References|