The Contribution of R Nitabuch to The World Obstetric Science

Volume 2 - Issue 3

Khasanov AA, Orlov YV* and Kuptsova AI

Received: January 18, 2019;   Published: January 23, 2019

DOI: 10.32474/OAJRSD.2019.02.000136

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Abstract

The adaptive conversion of spiral arteries is the essential part of pregnancy physiology and incomplete conversion is associated with preeclampsia and intrauterine growth restriction. Based on the study of an autopsy of a pregnant uterus, Raissa Nitabuch was the first who gave an accurate description of the uteroplacental circulation in main provisions of her doctoral thesis in 1887. In this thesis, the fibrinous layer in the decidua was identified as site of detachment of the placenta from the uterine wall after delivery of the baby. Although this was only an accidental finding, as “Nitabuch membrane” this fibrinous layer up to this day is associated with her name. It is unclear, why the much more important findings of the uteroplacental circulation never were published in a scientific journal. In view of the ongoing investigations on function and regulation of uteroplacental circulation, there can be no doubt, that an original publication of the findings of Raissa Nitabuch in a scientific journal today would be a Classic deserving to be revisited.

Keywords:Raissa Nitabuch; The Uteroplacental circulation; Fibrinoid of Nitabuch; History of medicine

Abstract| Introduction| The Fibrin layers| Conclusion| References|