Selective Androgen Receptor Modulators (SARMs) were discovered in the late 1990’s.They may have an application in treatments
of various diseases, including muscle wasting, cancer cachexia, breast cancer, osteoporosis, andropause and sarcopenia. In this minireview
the development, pharmacodynamics, and the phase 1 and 2 trial results of the SARMs are discussed with a special emphasis
on the illicit use of the SARMs.