Psychological Considerations to Use Alternative Therapiess
Volume 3 - Issue 3
Shah Murad1*, Fasiha Fatima2, A Qudoos3, Seema4, Abdul Ghaffar5 and Jamila Shah6
-
Author Information
Open or Close
- 1Professor of Pharmacology, IMDC, Pakistan
- 2Assistant Professor of Biochemistry at KIMS, Pakistan
- 3Associate Prof of Pharmacology at HBSMC Islamabad, Pakistan
- 4Gynecologist at NMC Karachi, Pakistan
- 5CWO at IMDC and DANTH, Pakistan
- 6Psychologist at BU Karachi, Pakistan
*Corresponding author:
Shah Murad, Professor of Pharmacology, IMDC, Pakistan
Received: January 03, 2020; Published: January 17, 2020
DOI: 10.32474/SJPBS.2020.03.000165
Full Text
PDF
To view the Full Article Peer-reviewed Article PDF
Abstract
Obesity is physical as well as psychological problem in human population. Dyslipidemia is alteration of normal levels of good and
bad cholesterol in human body. It can cause heart diseases like hypertension, cardiac arrhythmias, and heart attack. Niacin, Statins,
BABR and fibrates are used to normalize dyslipidemia. Medicinal herbs have been researched and found effective to normalize
plasma lipids with different characteristics.
Object of research: Aim of this research was to compare individual and combined effects of Ispaghola and Anjeer in primary
as well as secondary hyperlipidemia.
Design: It was single blind placebo-controlled research work, conducted from March 2018 to September 2018 at General
Hospital, Lahore, Pakistan.
Sample size: One hundred male and female hyperlipidemic patients were selected for research, age range from 20 to 65 years.
Inclusion criteria were primary, secondary hyperlipidemic patients. Written and explained consent was taken from all participants
and approved by research ethics committee of the hospital. Patients were divided in four equal groups, comprising 25 patients in
each group.
Method: Their baseline systolic/diastolic blood pressure and lipid profile was estimated and kept in individual’s folder. Group-I
was on Ispaghula 10 grams, group-II was on 10 grams Anjeer, and group-III was advised to take 10 grams Ispaghula, and 10 grams
Anjeer in combination for 3 months. Group-IV was on placebo therapy.
Results: After 3 months when results were compiled and analyzed statistically, it was observed that Ispaghula decreased LDL-c
significantly with p-value <0.05, Anjeer decreased LDL-c significantly with p-value <0.01. When both herbs were combinely given,
they reduced systolic BP with p-value <0.01, LDL-c reduced highly significantly with p-value <0.001, and HDL-c increased significantly
with p-value <0.05.
Conclusion: It was concluded from the study that Ispaghula and Anjeer have LDL-c lowering potential if given separately. When
used in combination they reduce systolic BP, LDL-c, and increase HDL-c.
Abstract|
Introduction|
Patients and Methods|
Results|
Key|
Discussion|
References|