Incidence and Clinical Outline of Hyponatremia in Psychiatric Inpatients: a Native Preliminary Evaluation

Volume 3 - Issue 2

Saeed Shoja Shafti*, Alireza Memarie, Masomeh Rezaie and Masomeh Hamidi

Received: October 21, 2019;   Published: October 31, 2019

DOI: 10.32474/SJPBS.2019.03.000157

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Abstract

Introduction: Hyponatremia is one of the most frequent ion and water disorders and severe hyponatremia is associated with well-known clinical symptoms and manifestations. In the present assessment the incidence and clinical profile of hyponatremia have been probed among a great sample of non-western psychiatric inpatients and compared with the available data in literature regarding prevalence and other associated clinical characteristics.

Methods: All inpatients with idiopathic hyponatremia during the last sixty-four months had been included in the present study. Clinical diagnosis, as well, was in essence based on ‘Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5)’. Statistical significance had been defined as a p value ≤0.05.

Results: While the annual incidence of hyponatremia in current evaluation was around 0.01%, the annual incidence of mortality due to hyponatremia was around 0.001%. It was significantly more prevalent among male psychiatric inpatients (p<0.04) and patients with duration of illness in excess of one year (p<0.04). Furthermore it was meaningfully more evident among schizophrenic patients (p<0.007), in comparison with remaining primary psychiatric disorders. There was no significant relationship between hyponatremia and symptomatic profile, or serum level of sodium and occurrence of seizure.

Conclusion: Hyponatremia was significantly more prevalent among male patients and cases with duration of illness in excess of one year. Furthermore it was meaningfully more evident among schizophrenic patients.

Keywords: Hyponatremia; Psychiatric disorders; Psychotropic drugs; Schizophrenia

Abstract| Introduction| Methods| Statistical Analysis| Results| Discussion| Conclusion| References|