Depression Revealing Primary Sjögren’s Syndrome with
Neurological Involvement
Volume 3 - Issue 5
Salem Bouomrani1,2*, and Ines Masmoudi1,2
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- 1Department of Internal medicine, Military Hospital of Gabes, Tunisia
- 2Sfax Faculty of Medicine, University of Sfax, Tunisia
*Corresponding author:
Saeed Shoja Shafti, University of Social Welfare and Rehabilitation Sciences [USWR] Razi Psychiatric Hospital
Tehran, Iran
Received: April 17, 2020; Published: April 27, 2020
DOI: 10.32474/SJPBS.2020.03.000175
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Abstract
Primary Sjögren’s syndrome (pSS) is the most frequent connective tissue disease but remains very underdiagnosed. Psychiatric
manifestations are classified among the central neurological disorders of pSS, and their prevalence is variously estimated according
to the series and the recruitment services: 20-70% of cases. They may be the predominant manifestations of the disease, but
pSS remains an underestimated cause of neuropsychiatric disorders. The inaugural psychiatric presentations of this disease are
exceptional and represent a real diagnostic challenge for clinicians. We report an original observation of depression as an initial and
isolated manifestation revealing neuro-Sjögren ina 60-year-old woman. Only a few similar sporadic cases were previously reported
in the world literature. As rare as it is, this clinical presentation of pSS deserves to be known by any healthcare professional.
Keywords: Depression; Primary sjögren’s syndrome; Neurological involvement; Neuro-sjögren; Behavior disorders
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