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ISSN: 2644-1373

LOJ Pharmacology & Clinical Research

Review Article(ISSN: 2644-1373)

A Brief Overview to TNF-a Inhibitors Therapy on Covid-19: Functions Inside Cell Cascades

Volume 2 - Issue 1

Serife Yerlikaya*

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    • Istanbul Medipol University, Regenerative and Restorative Medicine Research Center (REMER), Turkey

    *Corresponding author: Serife Yerlikaya, Istanbul Medipol University, Regenerative and Restorative Medicine Research Center (REMER), Kavacik North Campus, Kavacik-Beykoz/ISTANBUL, Turkey

Received: May 25, 2020;   Published: June 02, 2020

DOI: 10.32474/LOJPCR.2020.02.000129

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Abstract

Viral Covid-19 has spreaded all over the World only in a few months and caused much deaths. Covid-19 is belong to coronavirus family (called also SARS-CoV-2). Virus entry into cell occurs by unification with membrane receptors by releasing viral capsids or by endocytosis. TNF inhibitors aim to block receptors that bind to intracellular pathways as soluble form or by membrane bounding. Some TNF-α inhibitors have been used on severe Covid-19 patients nowadays.

Keywords: Receptor; Cell; Covid-19; İnhibitors

Abstract| Introduction| Tnf Inhibitors| Conclusion| Conflicts| References|

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