Cancer fatigue (CF) is defined as a great mental or physical
suffering persistent, or emotional and/or cognitive weakness. The
treatment of CF includes pharmacological and non-pharmacological
therapies. The Q10 strategies with promising results have also
been used. we aim to identify Q10 supplements that improve fatigue
in patients with cancer. The literature review was conducted
for Systematic Reviews and Meta- Analyses statement. Data were
obtained from PubMed, Scopus, MEDLINE, the Google and Google
Scholar. 893 studies were assessed, with cancer. The most commonly
used supplement that improves fatigue was co-enzyme Q10. Dietary
supplements or diet patterns are not often used to treat fatigue
in patients with cancer. The results of this review showed that Q10
could be used to treat CF in patients with cancer. The studies had
a low risk of bias with high-quality evidence on the efficacy of the
interventions in treating fatigue in cancer in the study population.