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- Department of Ophthalmology, Otorhinolaryngology and Head and Neck Surgery, University of São Paulo (FMRP-USP), Brazil
*Corresponding author:
Henrique Furlan Pauna, Department of Ophthalmology, Otorhinolaryngology and Head and Neck Surgery.
Ribeirão Preto Medical School, University of São Paulo (FMRP-USP), Ribeirão Preto, São Paulo, Brazil
Received: April 10, 2020; Published: June 15, 2020
DOI: 10.32474/SJO.2020.04.000187
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Abstract
Introduction: Neurological injury is an important cause of morbidity and post-operatory mortality in high complexity cardiac
surgery in children. The auditory brainstem response (ABR) evaluates specific areas of the brainstem. It provides useful information
about the functional state of the brain during important cardiovascular procedure.
Objective: To assess the progression in ABR waves as an indicator of neural integrity during controlled brain hypoxia-ischemia
among children undergoing to cardiac surgery with cardiopulmonary bypass (CPB).
Methods: Nine pediatric patients aged 0 to 2 years-old were included. The electrophysiological assessment – by means of ABR
– was performed at the operating room, during the following established steps of the cardiac surgery: general anesthesia (t0), CPB
and hypothermia (t1), and at the end of surgery (t2).
Results: Mean age of children was 10 months. Out of the 9 children, 3 were female and 6 were male. We observed increased
latency for waves I, III, and V. We also observed an increasing interpeak latency (I-III, I-V, and III-V) for both ears during CPB and
hypothermia (t1). Despite the increase in both average latencies and interpeak latencies, the values were not statistically significant.
Conclusion: No significant changes were found in the mean latencies and interpeak latencies of ABR during CPB and
hypothermia in complex cardiac surgeries included in the present study. ABR seems to be adequate to monitor patients during
general anesthesia.
Keywords: Auditory brainstem response; Cardiac surgery; auditory pathway; General anesthesia.
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