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ISSN: 2641-1709

Scholarly Journal of Otolaryngology

Research Articlet(ISSN: 2641-1709)

The Use of Auditory Brainstem Response (ABR) as Indicator of Neural Integrity in Newborn and Infants Submitted to High Complexity Cardiac Surgery

Volume 4 - Issue 3

Elaine Cristina Ramos, Henrique Furlan Pauna*, Jyrson Guilherme Klamt and Miguel Angelo Hyppolito

  • Author Information Open or Close
    • Department of Ophthalmology, Otorhinolaryngology and Head and Neck Surgery, University of São Paulo (FMRP-USP), Brazil

    *Corresponding author: Henrique Furlan Pauna, Department of Ophthalmology, Otorhinolaryngology and Head and Neck Surgery. Ribeirão Preto Medical School, University of São Paulo (FMRP-USP), Ribeirão Preto, São Paulo, Brazil

Received: April 10, 2020;   Published: June 15, 2020

DOI: 10.32474/SJO.2020.04.000187

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Abstract

Introduction: Neurological injury is an important cause of morbidity and post-operatory mortality in high complexity cardiac surgery in children. The auditory brainstem response (ABR) evaluates specific areas of the brainstem. It provides useful information about the functional state of the brain during important cardiovascular procedure.

Objective: To assess the progression in ABR waves as an indicator of neural integrity during controlled brain hypoxia-ischemia among children undergoing to cardiac surgery with cardiopulmonary bypass (CPB).

Methods: Nine pediatric patients aged 0 to 2 years-old were included. The electrophysiological assessment – by means of ABR – was performed at the operating room, during the following established steps of the cardiac surgery: general anesthesia (t0), CPB and hypothermia (t1), and at the end of surgery (t2).

Results: Mean age of children was 10 months. Out of the 9 children, 3 were female and 6 were male. We observed increased latency for waves I, III, and V. We also observed an increasing interpeak latency (I-III, I-V, and III-V) for both ears during CPB and hypothermia (t1). Despite the increase in both average latencies and interpeak latencies, the values were not statistically significant.

Conclusion: No significant changes were found in the mean latencies and interpeak latencies of ABR during CPB and hypothermia in complex cardiac surgeries included in the present study. ABR seems to be adequate to monitor patients during general anesthesia.

Keywords: Auditory brainstem response; Cardiac surgery; auditory pathway; General anesthesia.

Abstract| Introduction| Materials and Methods| Results| Discussion| Conclusion| Conflicts of Interest| References|

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