Bactericidal Biodegradable Films with Silver Nanoparticles for the Treatment of Burns

Volume 1 - Issue 4

Yunusov Khaydar Ergashovich*, Sarymsakov Abdushkur Abdukhalilovich and Rashidova Sayora Sharaphovna

Received: July 11, 2018;   Published: July 17, 2018

DOI: 10.32474/ANOAJ.2018.01.000118

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Silver nanoparticles stabilized in a solution of sodium carboxymethylcellulose (Na-CMC) with a degree of substitution of 0.65- 0.85 and degree of polymerization of 200-600 were synthesized. Physical, chemical properties, and antimicrobial activity of films prepared from sodium carboxymethylcellulose solutions containing silver nanoparticles were studied. The shapes, quantities, and sizes of the silver nanoparticles occurring in the sodium carboxymethylcellulose films were determined by atomic force microscopy and UV - spectroscopy. The shape, size, and quantity of silver nanoparticles determine their biological activity. At increase of the silver nanoparticle sizes of 5 up to 25 nm was found to enhance the microbicidal activitiy of the carboxymethylcellulose films.

Keywords: Silver; Nanoparticles; Sodium Carboxymethylcellulose; Degree of Substitution (Ds); Degree of Polymerization (DP)

Abstract| Introduction| Experimental| Results and Discussion| Conclusion| Acknowledgement| References|