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Lupine Publishers Group

Lupine Publishers

ISSN: 2641-1725

LOJ Medical Sciences

Letter to Editor(ISSN: 2641-1725)

Left Ventricular Hypertrabeculation / Noncompaction Associated with a SDHD Mutation

Volume 2 - Issue 3

Josef Finsterer1* and Sinda Zarrouk-Mahjoub2

  • Author Information Open or Close
    • 1Krankenanstalt Rudolf stiftung, Austria, Europe
    • 2Genomics Platform, Pasteur Institute of Tunis, Tunisia

    *Corresponding author: Josef Finsterer, Krankenanstalt Rudolf stiftung, Postfach 20, 1180 Vienna, Austria, Europe

Received: November 28, 2018;   Published: December 03, 2018

DOI: 10.32474/LOJMS.2018.02.000137

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In a recent article Alston et al. reported about a male neonate with mitochondrial disorder (MID) due to the novel homozygous mutation c.275A>G in the SDHD gene [1]. The only affected organ in this boy was the heart [1]. We have the following comments and concerns. In the vast majority of the cases noncompaction, also known as left ventricular hypertrabeculation (LVHT), is congenital [2] and LVHT can be detected already prenatally by fetal echocardiography [3]. Which was the reason why LVHT was recognised neither on fetal echocardiography nor on fetal cardiac MRI and not before postnatal echocardiography?

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