Left Ventricular Hypertrabeculation / Noncompaction Associated with a SDHD Mutation

Volume 2 - Issue 3

Josef Finsterer¹* and Sinda Zarrouk-Mahjoub²

Received: November 28, 2018;   Published: December 03, 2018

DOI: 10.32474/LOJMS.2018.02.000137

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Abstract

In a recent article Alston et al. reported about a male neonate with mitochondrial disorder (MID) due to the novel homozygous mutation c.275A>G in the SDHD gene [1]. The only affected organ in this boy was the heart [1]. We have the following comments and concerns. In the vast majority of the cases noncompaction, also known as left ventricular hypertrabeculation (LVHT), is congenital [2] and LVHT can be detected already prenatally by fetal echocardiography [3]. Which was the reason why LVHT was recognised neither on fetal echocardiography nor on fetal cardiac MRI and not before postnatal echocardiography?

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