Caudal Regression Syndrome: Case Report and Review Volume 4 - Issue 4

Sophie José¹*, Patricia Zelaya² and Cesar Trejo²

• ¹Ginecóloga Obstetra. Jefe departamento de Ginecología y Obstetricia, Hospital General Atlántida, USA
• ²Médico General, UNAH, USA

Received: February 06, 2020;   Published: February 11, 2020

*Corresponding author: Sophie José, Ginecóloga Obstetra. Jefe departamento de Ginecología y Obstetricia, Hospital General Atlántida. Honduras, USA

DOI: 10.32474/LOJMS.2020.04.000195

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Abstract

Introduction: Caudal regression syndrome is a congenital malformation ranging from agenesis of the lumbosacral spine to the most severe cases of sirenomelia. The etiology of this syndrome is not well known. Obstetric ultrasonography is the diagnostic tool of choice. Surviving infants have usually a normal mental function and they require extensive urologic and orthopedic assistance.

Clinical case: A 38-year-old pregnant woman, an obstetric ultrasound performed at 29 weeks gestation reports a single fetus, alive, axial cuts of the spine shows the absence of the sacral and coccyx portion. Lower hypoplasic limbs, contracted and crossed in Buddha position. Therefore, it is concluded as a fetus with suspected caudal regression syndrome. At 38 weeks gestation where the baby was born, with hypoplasia of the lower hemibody, narrow hips, distal leg atrophy, lower limbs in flexoabduction, bilateral equine foot, motor paresis of lower limbs, permeable anus. A total column radiograph confirms the interruption of the distal column with the absence of a sacral column, without continuity with the hypoplasic pelvis.

Discussion and conclusion: The antenatal screening will probably offer the opportunity for better management of this condition. Ultrasound and fetal MRI can be used to make a prenatal diagnosis. Early detection and prompt treatment are very important to decrease the risk of complications and improve the prognosis. A multidisciplinary approach is the task.

Keywords: Caudal regression syndrome; Sacral agenesis; Maternal diabetes; Congenital malformation.

Abstract| Introduction| Clinical Case| Discussion| Conclusion| References|