Groups 4 and 15 and Organotin Condensation Polymers
for The Treatment of Cancers and Viruses
Volume 1 - Issue 1
Charles E Carraher Jr1*, Michael R Roner2, Paul Slawek1, Francesca Mosca1, Jessica Frank1 and Lindsey Miller2
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- 1Florida Atlantic University, Department of Chemistry and Biochemistry, Boca Raton, FL 33431, USA
- 2University of Texas at Arlington, Department of Biology, Arlington, TX 76010, USA
*Corresponding author:
Charles E Carraher, Department of Chemistry and Biochemistry, Boca Raton, USA
Received: December 10, 2018; Published: December 12, 2018
DOI: 10.32474/MAMS.2018.01.000103
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Abstract
This short review describes the use of group 4 metallocenes, group 15 organometallics and organotin polymers in the
treatment of human cancer tumors and viruses. These metal-containing polymers show good inhibition of all the main group solid
tumors including pancreatic, lung, brain, breast, prostate and colon human cell lines. They also show inhibition of a variety of
viruses including zika, herpes and vaccinia viruses. Synthesis of the polymers is rapid employing interfacial polymerization and
commercially available reactants. They offer physicians a new class of drugs for the treatment of a variety of cancers and viruses.
Keywords: Cancer; Viruses; Interfacial polymerization; Brain cancer; Pancreatic cancer; Zika virus; Vaccinia virus, Breast cancer,
Herpes virus
Abstract|
Introduction|
Synthesis|
Cancer|
Viruses|
Why Polymeric Drugs?|
Summary|
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