Groups 4 and 15 and Organotin Condensation Polymers for The Treatment of Cancers and Viruses

Volume 1 - Issue 1

Charles E Carraher Jr¹*, Michael R Roner², Paul Slawek¹, Francesca Mosca¹, Jessica Frank¹ and Lindsey Miller²

Received: December 10, 2018;   Published: December 12, 2018

DOI: 10.32474/MAMS.2018.01.000103

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Abstract

This short review describes the use of group 4 metallocenes, group 15 organometallics and organotin polymers in the treatment of human cancer tumors and viruses. These metal-containing polymers show good inhibition of all the main group solid tumors including pancreatic, lung, brain, breast, prostate and colon human cell lines. They also show inhibition of a variety of viruses including zika, herpes and vaccinia viruses. Synthesis of the polymers is rapid employing interfacial polymerization and commercially available reactants. They offer physicians a new class of drugs for the treatment of a variety of cancers and viruses.

Keywords: Cancer; Viruses; Interfacial polymerization; Brain cancer; Pancreatic cancer; Zika virus; Vaccinia virus, Breast cancer, Herpes virus

Abstract| Introduction| Synthesis| Cancer| Viruses| Why Polymeric Drugs?| Summary| References|