Antibacterial Activity of Citrus Aurantifolia Leaves Extracts Against Some Enteric Bacteria of Public Health Importance

Volume 1 - Issue 2

Abubakar U Zage¹, Sani Tajo T² and Muhammad Ali³*

Received: December 08, 2018;   Published: December 20, 2018

DOI: 10.32474/MAMS.2018.01.000107

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Abstract

The study was conducted to determine the phytochemical composition and antibacterial activity of Citrus aurantifolia leaves extracts against clinical isolates of some enteric bacteria of public health importance. The result of phytochemical screening of the leaves extracts shows the presence of alkaloid, glycoside, saponin, tannin, flavonoid, steroids, terpenoid and phenol. The result of antibacterial efficacy of the extracts against the isolates indicated that the extracts were active against the isolates with higher activity in ethanol extract (with average zone of inhibition of 14.91mm) when compared to aqueous extract (12.67mm). The result of susceptibility of the isolates to the extracts showed Shigella was more sensitive to the extract with average zone of inhibition of 14.90mm, followed by Klebsiella (14.49mm), Escherichia coli (13.77mm) and Salmonella typhi with average zone of inhibition of 12.01mm. The minimum inhibitory concentration (MIC) of the extracts showed that dilutions of various concentrations of aqueous and ethanol of leaves extracts can inhibit the growth or kill the isolates at a concentration of between 2.125-20mg/ml. Statistical analysis of the results indicated that there is no significant different in the activity of the extracts against the isolates used at p<0.05. Findings from this study support the use of Citrus aurantifolia leaves extracts for medicinal purposes.

Keywords: Antibacterial activity; Citrus aurantifolia; Phytochemical; Enteric bacteria extract

Abstract| Introduction| Materials and Methods| Result| Discussion| Conclusion| Acknowledgement| References|