The Vitiated Ossein-Bacterial Osteomyelitis Volume 4 - Issue 5

Anubha Bajaj*

• Consultant Histopathologist, AB Diagnostics, India

Received:October 8, 2021Published: October 19, 2021

Corresponding author: Anubha Bajaj, Consultant Histopathologist, AB Diagnostics, India

DOI: 10.32474/IGWHC.2021.04.000199

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Abstract

Infection and inflammation of the bone, initially designated as osteomyelitis by Auguste Nelaton in 1844, occurs due to diverse pyogenic organisms, bacteria, fungi, and mycobacteria. The infection may extend to encompassing tissue and occurs as an acute or chronic inflammation.
Osteomyelitis is categorized into acute osteomyelitis, subacute osteomyelitis, or chronic osteomyelitis contingent to clinical duration of disease. Bacterial infection induces pyogenic osteomyelitis, a variant which is exceptionally delineated with the advent of contemporary antibiotics. Following the articulation of a sinus tract, an enlarged epidermal inclusion cyst layered with stratified squamous epithelium may be configured within the incriminated bone. Infrequently, the lining epithelium metamorphoses into well differentiated squamous cell carcinoma, a malignancy which is accompanied by a superior prognosis.

Abstract| Disease Characteristics| Disease Pathogenesis| Clinical Elucidation| Histological Elucidation| Differential Diagnosis| References|