email   Email Us: phone   Call Us: +1 (914) 407-6109   57 West 57th Street, 3rd floor, New York - NY 10019, USA

Lupine Publishers Group

Lupine Publishers

  Submit Manuscript

ISSN: 2637-4544

Interventions in Gynaecology and Women's Healthcare

Research Article(ISSN: 2637-4544)

Possible Role of Inadequate Quantities of Intra-Thyroidal Bromine, Calcium and Magnesium in the Etiology of Female Subclinical Hypothyroidism

Volume 1 - Issue 3

Zaichick Vladimir1* and Zaichick Sofia2

  • Author Information Open or Close
    • 1Radionuclide Diagnostics Department, Medical Radiological Research Centre, Russia
    • 2Laboratory of Dr. Gabriela Caraveo Piso, Feinberg School of Medicine, Northwestern University, USA

    *Corresponding author: V Zaichick, Medical Radiological Research Centre, Korolyev St.4, Obninsk 249036, Kaluga Region, Russia

Received: January 20, 2018;   Published: February 05, 2018

DOI: 10.32474/IGWHC.2018.01.000113

Full Text PDF

To view the Full Article   Peer-reviewed Article PDF


Objective: Subclinical hypothyroidism does affect fertility. The prevalence of subclinical hypothyroidism is 10-15 times more common in women than in men. Many chemical elements play important role in thyroid function and fertility. The aim of this exploratory study was to evaluate whether significant differences of chemical element contents exist between female and male thyroids and how they can be related to the etiology of subclinical hypothyroidism.

Methods: Thyroid tissue levels of Br, Ca, Cl, I, K, Mg, Mn, and Na were prospectively evaluated in 105 healthy persons (33 females and 72 males). Tissue samples were used for chemical element measurements, employing instrumental neutron activation analysis with high resolution spectrometry of short-lived radionuclides.

Results: It was found that the Br thyroid content of females was significantly higher than that of males, while the Ca and Mg contents were lower.

Conclusion: Inappropriate content of intra-thyroidal Br, Ca and Mg can be associated with the etiology of female subclinical hypothyroidism.

Keywords: Subclinical hypothyroidism; Female Thyroid; Chemical Elements; Neutron activation analysis

Abstract| Introduction| Material and Methods| Results| Discussion| Conclusion| Acknowledgement| References|