Utilization of Traditional Anticoagulation for Venous Thromboembolism in Patients with Liver Cirrhosis: Is It Safe?

Saad Qadwai¹*, Tayyaba Rehman² and Zeeshan Solangi³

Received: April 30, 2018;   Published: May 08, 2018

DOI: 10.32474/CTGH.2018.01.000104

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Abstract

Patients with liver cirrhosis are known to have increased risk bleeding particularly from gastrointestinal tract. However, recent literature has shown that patients with liver cirrhosis are also at increased risk of developing deep venous thrombosis and pulmonary embolism. Therefore, it is important to consider prophylactic and therapeutic anticoagulation in cirrhotic patients. In this article, we have reviewed the available literature on the safety and efficacy of the utilization of prophylactic and therapeutic anticoagulation in cirrhotic patients.

Abbrevations: INR: International Normalized Ratio; VTE: Venous Thromboembolism; DVT: Deep Venous Thrombosis; PE: Pulmonary Embolism; PTT: Partial Thromboplastin Time; LMWH: Low-Molecular-Weight Heparin; UFH: Unfractionated Heparin; CLD: Chronic Liver Disease

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