*Corresponding author:Tong Wang, Department of Cellular and Molecular Physiology, New Haven, USA
Received:March 09, 2019; Published: March 14, 2019
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Over the past several decades, great progress has been made on understanding mechanisms of gastric acid secretion for developing new anti-acid drugs. Until now most commonly used anti-acid drugs are histamine-2 receptor antagonists and proton pump inhibitors (PPIs) for patients to control acid related disease. However, several clinical limitations of these drugs had been reported. Recently, a new generation of potassium-competitive acid blockers (P-CABs) were launched for clinical use. It has been shown that these new drugs are more convenient and powerful to treat gastric acid-related diseases. In this article, we briefly reviewed the clinical use of this new anti-acid drug P-CAB.
Keywords:Potassium-competitive Acid Blocker; Potassium channel; H+/K+-ATPase
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