Diagnosis of Excess Bacterial Growth Syndrome in the Small Intestine in Patients with Bauhinia Deficiency and after its Surgical Correction as a Possible Cause of Toxic Endogenous Hepatitis

Volume 2 - Issue 4

Vladimir Leonidovich Martynov* and Natalia Vladimirovna Kazarina

Received:June 13, 2019;   Published: July 23, 2019

DOI: 10.32474/CTGH.2018.02.000142

Full Text PDF

To view the Full Article   Peer-reviewed Article PDF

Abstract

Objective: to determine the syndrome of excessive bacterial growth in the small intestine (SIBO) in patients with insufficiency of the bauhinia valve (NBZ) and after its surgical correction.

Methods of Examination: patients of the studied groups were examined using direct and indirect methods of diagnosis of SIBO. Bacteriological examination of ileal aspirate and other surgical material was performed. All patients underwent a hydrogen respiratory test with a load of lactulose and performed a qualitative reaction of urine to indican.

Characteristics of The Material: 50 patients were examined, of which 30 were included in the main group, who underwent surgical correction of NBZ - Bauginoplasty; 20 patients are included in the control group in which the ileocecal valve is consistent. Patients of the main group were examined before surgery and on the 7th and 45th day after Bauhinoplasty.

Main Results: all patients of the main group had SIBS of varying severity, in 80% of patients SIBS was localized in the distal small intestine. Patients with normal function of ileocecal valve syndrome of excessive bacterial growth did not suffer. Intraoperatively, 76% of patients showed signs of mesenteric mesentery of the small intestine, and the fact of bacterial translocation in SIBO was also confirmed. After 7 days after surgical correction of the Bauhinia valve, the normalization of peak and background excretion of hydrogen was observed in 37% of patients. For 45 days in all patients the hydrogen curve corresponded to the norm.

Conclusion: the deficiency of the bauhinia valve is obligately accompanied by the syndrome of excessive bacterial growth in the small intestine, surgical correction is an effective method for correcting the syndrome of excessive bacterial growth in patients with NBD.

Abstract| Introduction| Results and Discussion| Methodology| References|