Effect of Nicarbazin on Incubation Variables of Eggs from Creole Hens of Mexico

Volume 3 - Issue 2

Pro-Martínez A¹, Cuca-García JM¹, Matus-Aragón MA¹, Zárate-Contreras D¹, Sosa-Montes E², Osio-Orihuela L², Reyes-Bello JG² and González-Cerón F²*

04, 2019;   Published: December 18, 2019

DOI: 10.32474/CDVS.2019.03.000158

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Abstract

Nicarbazin (NCZ) is an equimolar complex of 4,4’-dinitrocarbanilide and 2-hydroxy-4,6-dimethylpyrimidine [1]. It is an anticoccidial agent used in the poultry industry. Its main function is to prevent multiplication and proliferation of parasites of Eimeria genus in the intestinal tract, avoiding tissue damage, decreased feed consumption, reduced nutrient absorption, dehydration, blood loss, skin depigmentation and susceptibility to other pathogens in birds [2]. Nevertheless, its application has not been entirely beneficial. Ott et al. [1] reported that feeding laying hens with 100 ppm or more of NCZ caused depigmentation of the brown shell and reduced hatchability in approximately 60%. Although the mode of action of NCZ for contraceptive activity is unknown, micrographs of vitelline membranes in mallards showed severe degenerative changes and preliminary in vitro studies indicated that it may increase intracellular calcium levels and early degradation of very low-density lipoproteins that comprise egg yolk [3].

Introduction| Materials and Methods| Results| Discussion | Conclusion| Acknowledgements| Conflict of Interest| References|