Pleomorphic Dermal Sarcoma: A Rare Diagnosis Volume 4 - Issue 1

Jordan Adams DO*, Crystal Fletcher Jones DO, Joshua Proffitt MD, Christopher Stumbo MD and Shakil Hossain OMS-IV

• Assistant Professor, University of Kentucky, College of Medicine, USA

Received:October 26, 2021;   Published: November 08, 2021

Corresponding author: Jordan Adams DO, Assistant Professor, University of Kentucky, College of Medicine, USA

DOI: 10.32474/JCCM.2021.04.000177

 

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Abstract

A 74-year-old man presented to the family medicine clinic with a 3-month history of lesion on his forehead. This has been getting larger but not bleeding or crusting. The patient has had no history of skin lesions before. The patient enjoys being outdoors, gardening, and working around his home. On physical examination there was a 1.5 x 1.0 cm nodular lesion present on the forehead above the brow and dark and red in color (Figure 1 A, B). There was no cervical lymphadenopathy. Clinical suspicion was squamous cell carcinoma or basal cell carcinoma, with this patient’s history. A 1.7 x 1.0 cm was submitted tagged on top. Further results of initial biopsy revealed dermal sarcoma. Histological analysis of the scalp lesion revealed spindle cell neoplasm comprised of hyperchromatic and vesicular nuclei with prominent nucleoli, and brisk mitotic activity. The lesion infiltrated into the subcutaneous tissue and shows perineural invasion. The neoplastic cells positive for CD10 and negative for AE1/AE3, P40, S100, SOX10, ERG, CD31, CD34, SMA, and Desmin (Figure 2). The lesion was confirmed to be pleomorphic dermal sarcoma (PDS). The patient was followed within clinic and the results were discussed. The patient was counseled on the importance of wearing sunscreen and hats when outside working. Another surgical biopsy with larger margins were taken and sent for pathology. Patient is clear of dermal sarcoma and is following up with oncology.

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