Gold Nanoparticle Sensor for The Detection of CKD and
Use of Nanomedicine in The Treatment of
Kidney Diseases
Volume 1 - Issue 2
Mohammad Gayoor khan1*, Umama Yezdani1, Shivam Choudghal2, Mayur Sadar3, Rana Sushma4 and Hari Baskar5
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- 1Department of Pharmacy, Truba institute of Pharmacy, India
- 2Department of Pharmacy Practice, MRM College of Pharmacy, India
- 3Department of Pharmacy Practice, ISF College of Pharmacy, India
- 4Department of Pharmacy, Anuradha College of Pharmacy, India
- 5Department of Pharmacy Practice, KMCH college of Pharmacy, India
*Corresponding author:
Mohammad Gayoor khan, Department of Pharmacy, Truba institute of Pharmacy, Bhopal, Madhya Pradesh,
India
Received: December 14, 2019; Published: January 07, 2020
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Abstract
Aim: To study the use of nanotechnology in the diagnosis by the mean of breath and its treatment with nano medicine.
Material and Method: The study was carried out in 40 patients of different age groups and their breaths were exhaled. These
breaths were analyzed by the use of sensors which were basically functionalized with gold nanoparticles. Sensitivity and specificity
with relation to CKD patient classification according to estimated glomerular filtration rate were determined using cross-validation.
The medicine was induced after the proper analysis of the target.
Results: It was found that the sensors were very useful when 2-3 nanoparticles were used together, and it showed that in
between stage 1 and 2 CKD with an accuracy of 60% and in between stage 4 and stage 5 of CKD accuracy was 67%. There were
various substances in breath which could identify many toxins which were accumulated due to kidney function loss. It was found
that when treatments were provided using the nanomedicine the administration of the drug to target site was getting easy and
many side effects due to drugs were avoided and was found to be a very useful method in the treatment of the patients with kidney
diseases.
Conclusion: Nanotechnology in terms of both gold nanoparticles as well as nanomedicine has been proven to be a cost effective,
reliable and a great source to target the tissues which need to be treated and shows a greater future potential in the diagnosis and
treatment of kidney diseases.
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