email   Email Us: phone   Call Us: +1 (914) 407-6109   57 West 57th Street, 3rd floor, New York - NY 10019, USA

Lupine Publishers Group

Lupine Publishers

  Submit Manuscript

ISSN: 2690-5760

Journal of Clinical & Community Medicine

Research Article Open Access

Gold Nanoparticle Sensor for The Detection of CKD and Use of Nanomedicine in The Treatment of Kidney Diseases

Volume 1 - Issue 2

Mohammad Gayoor khan1*, Umama Yezdani1, Shivam Choudghal2, Mayur Sadar3, Rana Sushma4 and Hari Baskar5

  • Author Information Open or Close
    • 1Department of Pharmacy, Truba institute of Pharmacy, India
    • 2Department of Pharmacy Practice, MRM College of Pharmacy, India
    • 3Department of Pharmacy Practice, ISF College of Pharmacy, India
    • 4Department of Pharmacy, Anuradha College of Pharmacy, India
    • 5Department of Pharmacy Practice, KMCH college of Pharmacy, India

    *Corresponding author: Mohammad Gayoor khan, Department of Pharmacy, Truba institute of Pharmacy, Bhopal, Madhya Pradesh, India

Received: December 14, 2019;   Published: January 07, 2020

Full Text PDF

To view the Full Article   Peer-reviewed Article PDF


Aim: To study the use of nanotechnology in the diagnosis by the mean of breath and its treatment with nano medicine.

Material and Method: The study was carried out in 40 patients of different age groups and their breaths were exhaled. These breaths were analyzed by the use of sensors which were basically functionalized with gold nanoparticles. Sensitivity and specificity with relation to CKD patient classification according to estimated glomerular filtration rate were determined using cross-validation. The medicine was induced after the proper analysis of the target.

Results: It was found that the sensors were very useful when 2-3 nanoparticles were used together, and it showed that in between stage 1 and 2 CKD with an accuracy of 60% and in between stage 4 and stage 5 of CKD accuracy was 67%. There were various substances in breath which could identify many toxins which were accumulated due to kidney function loss. It was found that when treatments were provided using the nanomedicine the administration of the drug to target site was getting easy and many side effects due to drugs were avoided and was found to be a very useful method in the treatment of the patients with kidney diseases.

Conclusion: Nanotechnology in terms of both gold nanoparticles as well as nanomedicine has been proven to be a cost effective, reliable and a great source to target the tissues which need to be treated and shows a greater future potential in the diagnosis and treatment of kidney diseases.

Abstract| Introduction & Objectives| Material and Method| Results| Discussion| Conclusion| References|


Online Submission System

Drag and drop files here


Browse Files
( For multiple files submission, zip them in a single file to submit. For file zipping software Download )