w Phytochemical, Antimicrobial Potential and Antifungal Activities Stem Bark Extract of Boswellia Ovalifoliolata
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ISSN: 2637-4609

Archives of Organic and Inorganic Chemical Sciences

Research Article(ISSN: 2637-4609)

Phytochemical, Antimicrobial Potential and Antifungal Activities Stem Bark Extract of Boswellia Ovalifoliolata

Volume 1 - Issue 5

Teklit Gebregiorgis1* and Birhanu nigussie2

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    • 1 Mekelle University, Department of Chemistry, Mekelle, Ethiopia
    • 2 Department of pharmacy, Addsia Abeba University, Ethiopia

    *Corresponding author: Teklit Gebregiorgis, Mekelle University, Department of Chemistry, Mekelle, Ethiopia

Received: February 06, 2018;   Published: February 19, 2018

DOI: 10.32474/AOICS.2018.01.000122

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Abstract

This study was carried out with an objective to investigate the antibacterial and antifungal potentials of Stem bark of Boswellia ovalifoliolata (BO). The aim of the study is to assess the antimicrobial activity and to determine the zone of inhibition of extracts on some bacterial and fungal strains. In the present study, the microbial activity of ethanolic extracts of stem bark of Boswellia ovalifoliolata. (Endemic medicinal plant) was evaluated for potential antimicrobial activity against medically important bacterial and fungal strains. The antimicrobial activity was determined in the extracts using agar disc diffusion method. The antibacterial and antifungal activities of extracts (5, 25, 50, 100, 250μg/ml) of Boswellia ovalifoliolata. Were tested against two Gram-positive Staphylococcus aureus, Streptococcus pyogenes two Gram-negative-Escherichia coli, Pseudomonas aeruginosa human pathogenic bacteria. Three fungal strains Aspergillus niger, Aspergillus clavatus, Candida albicans. Zone of inhibition of extracts were compared with that of different standards like ampicillin, ciprofloxacin, norfloxacin, and chloramphenicol for antibacterial activity and nystatin and griseofulvin for antifungal activity. The results showed that the remarkable inhibition of the bacterial growth was shown against the tested organisms. The phytochemical analyses of the plants were carried out. The microbial activity of the Boswellia ovalifoliolata was due to the presence of various secondary metabolites. Hence, these plants can be used to discover bioactive natural products that may serve as leads in the development of new pharmaceuticals research activities.

Keywords: Boswellia ovalifoliolata; in vitro Antibacterial activity; Antifungal activity; Secondary metabolites.

Abstract| Introduction| Material and Methods| Results and Discussion| Conclusion| References|

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