Hypertrophic cardiomyopathy (HCM) is the most common cardiac disease affecting the cardiac muscle. It can manifest in
different forms with or without left ventricular outflow obstruction, with or without right ventricle involvement. Forms with
biventricular hypertrophy seem to have poor prognosis. In our case, we describe a young patient with sarcomeric biventricular
hypertrophic cardiomyopathy (MYH7 mutation), the poor prognosis of this form and strategies options adopted after failure of
medical treatment. It is not always easy the management of hypertrophic cardiomiopathy, after medical treatment failure, especially
in children. In some cases, heart transplantation is the only one therapeutic option.
Keywords: Hypertrophic Cardiomiopathy; Right Ventricular Hypertrophy; Heart Transplantation