Advocating the Need for a CT Coronary Angiography Screening Program for Prevention of Coronary Artery Disease in High – Risk Population & guiding future pharmaceutical research

Abhinav Aggarwal*

Received: May 25, 2018;   Published: May 29, 2018

DOI: 10.32474/ACR.2018.01.000108

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Abstract

Cardio-vascular disease (CVD) is one of the major causes of morbidity and mortality in Europe and world. It accounts for majority of spend on healthcare in European Union countries and is the second on the list. Non-calcific plaques form the majority of plaques and non-calcific & mixed plaques are responsible for majority cases of severe stenosis. Since non-calcific and mixed plaques are resolvable by intensive statin therapy and are responsible for majority of severe acute coronary related events (vulnerable plaques), coronary artery disease is preventable if proper screening is done which should lead to significant decrease in economic burden of cardio-vascular & cerebro-vascular diseases. These findings warrant a discussion on systemic screening program for the same through CT coronary angiography.

Abbrevations: CVD: Cardio-vascular disease; EU: European Union: EHN: European Heart Network; A&E: accident & emergency; GPs: General practitioners; CTCA: Computed Tomography Coronary Angiography screening

Abstract| Introduction| Etiology/Disease Burden Of CVD| Pathogenesis Of CVD| Cost of CVD| Taking Inspiration From Other Successfully Implemented Screening Programs| Role of Statins And Ideas For Further Pharmaceutical Research| Cost of Prospected Screening Program| References|