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ISSN: 2638-5945

Open Access Journal of Oncology and Medicine

Research Article(ISSN: 2638-5945)

Radiofrequency Ablation for Atypical Cartilaginous Tumors is safe and effective: analysis of 189 consecutive cases?

Volume 3 - Issue 5

Nijland H1, Overbosch J2, Ploegmakers JJW1, Kwee TC2 and Jutte PC1

  • Author Information Open or Close
    • 1Department of Orthopaedic Surgery, University Medical Center Groningen, The Netherlands
    • 2Department of Radiology, University Medical Center Groningen, The Netherlands

    *Corresponding author:Nijland H, Department of Orthopaedic Surgery, University Medical Center Groningen, The Netherlands

Received: June 12, 2020;   Published: June 29, 2020

DOI: 10.32474/OAJOM.2020.03.000172

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Objective: The purpose of this study was to investigate the efficacy and safety of radiofrequency ablation (RFA) as a less invasive treatment alternative for atypical cartilaginous tumors.

Materials and methods: Data of all consecutive RFA procedures for atypical cartilaginous tumors between 2007-2018 were analyzed, including temperature, amount of needle positions and ablation time per position. Tumor volume was measured on preoperative MRI and ablation zone was assessed on 3-month postprocedural MRI. RFA outcome parameters were ablation result (R0: complete with margin (≥2mm), R1: complete without margin (<2mm) and R2: incomplete) and occurrence of complications.

Results: In 84.4% of cases complete ablation was achieved (66.7% R0, 17.7% R1). In 15.6% of procedures ablation was incomplete (R2). No recurrences were seen after R0/1 ablations (with minimum two years follow-up). R0 was achieved significantly more frequent in smaller tumors (p = .027, odds ratio (OR) = 1.04 (per cm3) and with longer ablation time per needle (p = .048, OR = .894). Temperature >80°C (p = .026, OR = 7.57) resulted in more complete (R0 or R1) ablations without increasing complication rate (p = .579) compared to temperature of 71-80°C. In 15 procedures (7.9%) a complication occurred.

Conclusion: RFA provides promising results for treatment of atypical cartilaginous tumors with complete ablation (R0, R1) in 84.4% of procedures. Complication rates are comparable with open surgery and the amount of fractures is lower. These encouraging data support the potential of RFA to replace more invasive surgical approaches.

Abstract| Introduction| Method| Results| Discussion| Conclusion| Contributors Statement| Disclosure statement| References|


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