Plasma Lysophasphatidic Acid Level: A Diagnostic
Tool and Benchmark for Ovarian Cancer Management

Muhammad Imran Qadir; Saima Saadat

Email Us: info@lupinepublishers.com phone

Call Us: +1 (914) 407-6109 57 West 57th Street, 3rd floor, New York - NY 10019, USA

Submit Manuscript

ISSN: 2638-5945

Open Access Journal of Oncology and Medicine

Review Article(ISSN: 2638-5945)

Plasma Lysophasphatidic Acid Level: A Diagnostic Tool and Benchmark for Ovarian Cancer Management

Volume 1 - Issue 5

**Muhammad Imran Qadir¹* and Saima Saadat²**

Author Information Open or Close
- ¹Institute of Molecular Biology & Biotechnology, Bahauddin Zakariya University, Multan, Pakistan
- ²Faculty of Pharmaceutical Sciences, Government College University, Faisalabad, Pakistan
*Corresponding author: Muhammad Imran Qadir, Institute of Molecular Biology & Biotechnology, Bahauddin Zakariya University, Multan, Pakistan

Received: May 24, 2018; Published: May 30, 2018

DOI: 10.32474/OAJOM.2018.01.000122

Full Text PDF

To view the Full Article Peer-reviewed Article PDF

Abstract

In ovarian cancer there is formation of tumor cells in ovarian tissues. Lysophosphatidic acid (LPA) motivated cell proliferation, migration and endurance by acting on its cognate G-protein-coupled receptors. Lysophosphatidic acid (LPA), present in ascitic fluid, motivates the enlargement of malignant ovarian tumors by raising the appearance of vascular endothelial growth factor (VEGF) in ovarian cancer cells. Ovarian cancer cell progress is repressed by alendronate, a nitrogen containing biophosphate which attenuate the establishment of Rho by blocking the mevalonate pathway.

Editorial Manager:

Lori Donald

Email:

oncology@lupinepublishers.com

oncology@lupinepublisher.co

Track Your Article

Top Editors

Mark E Smith

Bio chemistry
University of Texas Medical Branch, USA
Lawrence A Presley

Department of Criminal Justice
Liberty University, USA
Thomas W Miller

Department of Psychiatry
University of Kentucky, USA
Gjumrakch Aliev

Department of Medicine
Gally International Biomedical Research & Consulting LLC, USA
Christopher Bryant

Department of Urbanisation and Agricultural
Montreal university, USA
Robert William Frare

Oral & Maxillofacial Pathology
New York University, USA
Rudolph Modesto Navari

Gastroenterology and Hepatology
University of Alabama, UK
Andrew Hague

Department of Medicine
Universities of Bradford, UK
George Gregory Buttigieg

Maltese College of Obstetrics and Gynaecology, Europe
Chen-Hsiung Yeh

Oncology
Circulogene Theranostics, England
Emilio Bucio-Carrillo

Radiation Chemistry
National University of Mexico, USA
Casey J Grenier

Analytical Chemistry
Wentworth Institute of Technology, USA
Hany Atalah

Minimally Invasive Surgery
Mercer University school of Medicine, USA
Abu-Hussein Muhamad

Pediatric Dentistry
University of Athens , Greece