New Ways to Look at Blood Pressure Volume 3 - Issue 3

Shah Murad¹*, Adnan Shafique², Amarlal Ghurbakhshani³, Seema Shah Murad⁴, Abdul Ghaffar⁵ and Jamila Shah⁶

• ¹Department of Pharmacology, Islamabad, Pakistan
• ²Clinical Pharmacist at MCC Pharmacy, ISD, Pakistan
• ³Department of Physiology at CMC Larkana Sindh, Pakistan
• ⁴Department of Gynecologist at NMC, Karachi, Pakistan
• ⁵CWO at IMDC and DANTH, Islamabad, Pakistan
• ⁶Department of Psychologist at BU Karachi Pakistan

Received:December 17, 2019   Published: January 06, 2020

Corresponding author: Shah Murad, Department of Pharmacology, IMDC, Islamabad, Pakistan

DOI: 10.32474/OAJOM.2020.03.000163

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Abstract

There are ethnic-based medicinal herbs which can be used to treat or prevent CAD with narrow to moderate range of statistical significance. We compared Rosuvastatin 10 mg with Indian dates (Jujubes) as hypolipidemic agents. This research was conducted at Ghurki Trust Teaching Hospital, jalo park, Lahore, Pakistan. Duration of study was two months. Twenty to seventy years old 60 hyperlipidemic patients of both genders were included in research work with written consent. We divided these patients in two equal groups. Group-I was advised to take Tablet Rosuvastatin 10 mg, twice daily for two months. Group-II was advised to take 500 grams Indian dates for two months. Their baseline parameters like LDL-cholesterol, HDL-cholesterol, systolic/diastolic blood pressure was determined in the hospital laboratory. Separate file was maintained for their name, age, sex, occupation, and address. After two months therapy we compiled data related to tested parameters. Paired t-test was applied to compare changes in all parameters. Their mean values with ± SD before and after treatment were compared and analyzed statistically. It was observed that Rosuvastatin significantly decreased systolic/diastolic blood pressure, LDL-cholesterol, and increased HDL-cholesterol in 27 hyperlipidemic/hypertensive patients. Indian dates used in 30 hyperlipidemic patients significantly decreased systolic blood pressure, and LDL-cholesterol, but insignificant changes were seen in diastolic blood pressure, and HDL-cholesterol. We concluded from the research work that Rosuvastatin is potent hypolipidemic and hypotensive medicine as compared to indian dates.

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