One or two years before I were considering the test of
culture and sensitivity C/S in all specimens including urine is the
optimal test or the last measure act in reaching the diagnosis for
any. Recently this idea had gone away completely not due to the
unknown extent of false negative and positive activity of the
antibiotics due to vivo and vitro affairs. It is due to a fact that the
revealed bacteria are not the point of our mystery especially in
chronic repetitive urinary tract infection which may end in renal
failure. The bacteria mentioned in the result forma or paper are
what I term them as ‘’ Bad face or Quarrelsome face’’ this means if
someone with this adjective is a person who is sent by someone to
another someone to e.g. collect a post-due dept the owner failed to
have it in usual fashion, or better when a gang boss is behind the jail
bars send his outside guys to perform actions planed by him. This
later example is the most correct description to the fact I want to
reach which is the bacteria in the C/S result are the extra-cellular
bacteria ECB where as the real problem confined in the depth of
the cells where the intra-cellular bacteria ICB reside. The cells of
urinary tract lining or underneath.
Take this for example ( however I said recently ) I started
to realize it may be got mature or hundred percent sure after
accumulation of data that this idea is a fact. The example is; around
ten years ago me and some surgeons and physicians went as a team
of experts to some country to correct some health issue, three days
post arrival one of our team which is a consultant urosurgeon asked
for return home, I asked him what the cause could be, he replied with
sadness that his mother suffer from chronic urinary tract infection
and she is now tired so he need to find some solution especially
it is resistant to recover. Really I laughed reflexly and told him we
come to this country as expert to solve their problems while your
mother had chronic UTI and you cannot put an end for it! He made
no other response other than the first by saying in sad manner and
his head inclined to the earth ‘ that is right I cannot help my mother
further’ then me as a friend try to help asked him ‘’ did you do C/S”
he said yes, what was the result ? he replied E. coli. I commented
that he should consider Brucellosis to treat his mother with because
Brucella is the ICB which sit inside the lining cells and make certain
environment encourages the growth of certain biotic life and here
we find E. coli as a “ bad face” to mis-lead and direct our attention
away from it. Certain environment conditions make a given growths
like a damp room find into it spider webs which keeps increase as
time passes.
This consultant urosurgeon did not make any objection on
my instruction and I felt some comfort from his side as if I gave
some exit however I am neurosurgeon and were not a consultant
at that time. From where this principle came for me! More than
twenty years ago I adopted the digging into the biological basis of
neurosurgical pathologies. At the beginning it was based on clinical
trial treatment after pointing the that Brucella what is behind the
symptomatology and hence the pathology behind clinical condition
( lab is not reliable as serological test where if negative all what
we do is missing the patient’s real problem to go to palliative and
symptomatic measures) the results in my field were excellent
starting with spine problems like low-back pain. As time and
positive results pass on a new facts spring on earth like some other
health problems that were accompany the treated issue faiding out
to show in analysis the main issue and these faiding other health
problems are mere pictures or more precisely are complications to
the main health problem which in end one realizes it is a chronic
or sub-acute bacterial systemic infection. As time passes more and
more organs and tissues become involved. Lately PCR open tissue
examination for Brucella proved that this idea is a fact where the
results at the beginning were 25% positive for Brucella in my
patients when the tissue where taken from Sacroiliac joint. Then
around 60% positive when Trapezius muscle open biopsy was
considered. By admitting screen molecular test with Micro-array
and I enlisted around fifteen ICB now for direct sampling like spine
and brain and so for my cases which biologically shows the other
pathologies share similar. Urinary bladder cystoscope or renal
biopsies for PCR screen may reveal this fact either. M. tb. And others
are interpretation difficulty for me now where they emerge on my
field.