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ISSN: 2644-1373

LOJ Pharmacology & Clinical Research

Research ArticleOpen Access

Development and Characterization of Herbal Formulation Containing Aqueous Extract of Clitoria Ternatea Linn. (Flowers) for the Treatment of Vaginal Infection Volume 2 - Issue 4

Urvashi Sharma* and Sumeet Dwivedi

  • University Institute of Pharmacy, Oriental University, Indore, India

Received: April 08, 2021   Published: April 19, 2021

Corresponding author: Urvashi Sharma, University Institute of Pharmacy, Oriental University, Indore, India

DOI: 10.32474/LOJPCR.2021.02.000143

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Abstract

Among several gynecological problems, vaginal infection (vaginitis) is the most common problem that women face in their life span, caused by Candida species. Candida albicans, a fungus which is responsible for the vaginal infection and to cure it, innumerable herbs are available which were earlier frequently used by the local civilization but now their demand is increasing in global market also. Numerous studies have confirmed the use of Clitoria ternatea as an antimicrobial agent, so the present work has been undertaken to explore the anti-candida activity of the plant. Along with that, formulation of herbal cream was aimed. In this study, the herbal creams (HC1-HC8) were formulated and evaluated possessing aqueous extract of flowers of Clitoria ternatea Linn. and the results revealed the satisfactory results when compared with standard drug. The results of formulation with code HC5 were found to be very promising and excellent of all herbal cream formulated. Ensuring biological activity for any formulation is of prime interest to reveal and prove the efficacy of formulated dosage form. In view of the same, Herbal Creams (PHC) were prepared and subjected to anti-candida activities, where PHC of HC5 was evaluated for anti-Candida activity as an optimized preparation. From the results obtained, it was concluded that the PHC (HC5) have optimum anti-candida activity when compared with standard formulation (MCC) and may be used for the treatment of vaginal infection. Moreover detailed clinical approaches need to establish for the formulation of safe and effective drugs

Keywords:Clitoria ternatea; Anti-fungal; Vaginal infection

Abstract| Introduction| Materials and Methods| Determination of Type of Emulsion| Results and Discussion| Conclusion| References|

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